Chelsea and Sevilla failed to score a single goal as both teams who are favourite to top the group played goallessly.
The Blues welcomed the Europa League champions to Stamford Bridge and they were lucky to share the spoils.
Debutants Rennes and FC Krasnodar’s also played a 1-1 draw in their first Uefa Champions League outing.
Sehr Guirassy gave the French side the lead before Cristian Ramirez scored to share the spoils at the Roazhou Park in France.
Group F
Club Brugge stunned Zenit St Petersburg 2-1 away to kick off the new campaign on winning note.
Nigerian International Emmanuel Dennis broke the deadlock for Club Brugge.
Zenit levelled thanks to an own goal from Ethan Horvath.
But Charles De Kelelaere goal sealed the victory for the Belgian side.
Lazio claimed a resounding 3-1 victory against Dortmund as Ciro Immobile orchestrated the downfall of his former club.
The forward scored just 6 minutes into the game before Marwin Hitz own goal gave the Serie A side a 2-0 lead.
Erling Braut Halland gave Dortmund the hope a possible comeback as he scored in the 71 minutes.
Immobile then provided assist for Jean Akpa-Akpro who scored to make it 3-1
Group G
Alvaro Morata fired Juventus to a perfect start as they claimed a 2-0 away win against Dynamo Kyiv.
Morata scored twice in the 46th and 84th minute to give Andrea Pirlo his first Uefa Champions League win.
At Camp Nou, Lionel Messi set a new record as the first player to score in 16 consecutive Uefa Champions League season.
The Argentine broke the deadlock for the Blaugrana as he scored from the spot in a six-goal thriller with the hosts winning 5-1 against Ferencravos.
Ansu Fati doubled the lead before the break to make it 2-0
Philippe Coutinho found his name in the scoresheet to extend the lead to 3-0.
The Catalans were reduced to 10-man after Gerard Pique was sent off for fouling Ferencravos player inside the box.
Igor Khamatin scored from the spot to give the Hungarian side the hope of a possible come back.
But Barca debutant, Pedri scored to make it 4-1 before Ousmane Dembele scored the fifth goal to cap what was already a stroll for Barcelona.
Group H
Manchester United capped their return to the Champions League with another impressive away win against Paris Saint-Germain at the Parc Des Princes in France.
Bruno Fernandes who captained the Red Devils scored from the spot before Anthony Martial own goal levelled for PSG.
Marcus Rashford scored a late goal in the 87 minutes to give Ole Gunnar Solksjaer the win.
It was the second time Rashford will be scoring against the French after boa late minute goal sent PSG packing from the competition in the 2018/2019/ season.
In Germany, last season semi-finalist RB Leipzig won 2-0 at home against Istanbul Basaksehir.
A brace from Angelino was enough to hand Leipzig a perfect start to the competition.