Premier League leaders Arsenal missed a chance to seal top spot in Europa League Group A as they lost to PSV Eindhoven in the Netherlands.

Arsenal have failed to win their past two games after a run of eight straight wins in all competitions

The Gunners only needed a point to go straight through to the last 16 next March.

But Joey Veerman’s first-time finish from 16 yards and a header by substitute Luuk de Jong – after a mistake by keeper Aaron Ramsdale on his European debut – saw Mikel Arteta’s side lose in Europe for the first time this season.

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As Arsenal was soundly defeated, PSV, spearheaded by former Manchester United star Ruud van Nistelrooy, also had three goals disallowed for offside.

To ensure a spot in the round of 16, the Gunners must defeat Zurich in their final group match on Thursday at Emirates Stadium (20:00 GMT).

If they fail to win and PSV beat Bodo/Glimt in Norway, Arsenal will face two extra games in the knockout round playoffs, where teams that finish third in the Champions League group stage, including Barcelona, drop into.

They are still favorites to win the group, but with their second loss in as many games (16), Arteta currently doesn’t seem to be in a position to rest some of their key players before the heavyweight London derby at Chelsea on November 6.